Base sequence differences between the RNA components of Harvey sarcoma virus
نویسندگان
چکیده
منابع مشابه
An altered DNA sequence encompassing the ras gene of Harvey murine sarcoma virus.
The DNA fragment encompassing the ras gene of Harvey murine sarcoma virus was sequenced and assigned the coding region of a transforming protein, p21, to the sequence. Examination of nucleotide sequence, taken together with the result of analysis of the ras mRNAs (1), has revealed that p21 is encoded from a continuous coding region starting with the 5' proximal initiation codon but not a proces...
متن کاملFunctional analysis of the murine sarcoma virus RNA packaging sequence.
We investigated the features of the Moloney murine sarcoma virus leader sequence necessary for RNA packaging function by using a deletion analysis approach. We found that sequences that extend beyond those characterized genetically in previous reports are important for optimal packaging efficiency. A fragment covering a minimum of four potential stem-loop structures is required for the shortest...
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Using a novel chemical tritium derivative method, we have determined the base composition of 4S RNA isolated from an RNA tumor virus, the avian myeloblastosis virus, and from normal and neoplastic host cells. Extensive differences were detected, particularly with respect to the amount of methylated bases in the viral RNA. The viral 4S RNA, which fulfills the criteria for designation as transfer...
متن کاملHarvey sarcoma virus: a second murine type C sarcoma virus with rat genetic information.
The nucleic acid sequences found in the Harvey strain of murine sarcoma virus have been analyzed by RNA.[(3)H]DNA and [(3)H]RNA.DNA hybridization techniques. The Harvey strain of murine sarcoma virus has been found to possess at least two sets of nucleic acid sequences. One set of sequences is contained in the Moloney strain of mouse type-C virus, and the other set is contained in DNA transcrip...
متن کاملIdentity of the two 8S RNA components of the mouse sarcoma virus (Moloney).
The two 8S A and B RNAs of the Mouse Sarcoma Virus (Moloney) can be converted by heating into a homogeneous population. After digestion with T(1) RNAse, they give identical fingerprints. It is concluded that these two molecules represent conformational isomers of the same molecular species.
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1975
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.16.3.749-753.1975